I'm currently prepping to breed alot of hype strains with CBD strains, like wedding cake, GMO, purple soda breath, oaxacan, a rare cut of GDP, herijuana, black domina the list is endless.
I dont care much for the cali hype strains for my own meds though. So I grow mainly heavy indicas.
F1 is basically the first offspring of whatever you breed, so its unstable sometimes and can have many many different phenos. So you grow them, select whatever plants have the desired traits, then those get used to breed again. Its along process but it's very dependant an the strains. Proper breeders also stress test the fuck outta the f1 phenos to make sure you have a quality seed to begin with. But f1s are worthless. If you charge for f1s your an asshole. As you breed again and again it's just basically f1(generation 1), f2 (generation 2) and so on and so forth. You can def sell f2s but I prefer to work work work and get to f4 so you have very good quality, good resilience and will grow very well and predictable.
Breeding is alot of fuckin work, and requires alot of knowledge and space. But its worth it for those that need quality meds.
That being said, many older strains are fine untouched. Like say northern lights, or SFV Og, although they to get bred into other strains, the originals are fantastic
But cannabis is crazy. You can make whatever the fuck you want if ya want to.
And I already have unreleased strains bred to f1s and f2s, so if SLAP wants it's own strain, name it and I'll take donations to send it out!
Start picking names lol