It depends where you are skating.
I have boards built up right now with SPF, STF 103, STF 99, F4 101, F4 99 and NFG 95. All have a surface and type of skating that they are better at.
SPF are fastest in baby smooth transition parks. Fucking horrible outside of this, but amazing in.
STF 103 are fast and can slide in baby smooth "street" parks. These were my go-to for years - but I am using them just occasionally now.
F4 101 are probably my favorite all around, are more comfortable than the harder Bones - but aren't quite as fast. If I had to choose one wheel for everywhere it would probably be this.
STF 99 are a bit grippier than F4 99, so good if you are skating super slick surfaces like a brand new park or dusty indoor. They are also good in the street - but don't slide quite as well as an F4 99.
F4 99 are good in the streets, but I find them slow in super smooth parks so seldom skate them.
NFG are good in crust.
I have flat spotted SPF, STF 103 and F4 101 multiple times each. All are good at resisting, but none are bulletproof.