So, I recently set up a set of Conical Fulls I rode for two months last winter (indoor park). I cleaned my bearings and tried to put them back and I found in one wheel they barely went in. I had to put a lot more effort to get the bearings in that one wheel than the others. I also seemed to spin worse (differently). Do I have a defect wheel now? I read somewhere here people having at least one bad wheel in a new set.
There were some issues with the bearing seat being a bit off in some wheels from a while back. I had a set with that issue, returned for a replacement set from the shop, no issues - just the plain blue logo graphic Conical Full 54 mm 99 duro wheels. Others also found one wheel (usually just one but sometimes two) in various sets had a defect with something similar.
The best way to check is put a bearing on an axle and put the wheel on it, seated fully, then spin the wheel. Take it off, removing the bearing, turn it over and try it again the other way. If the wheel spins a bit off center while on either bearing then it is most likely going to be something like that mentioned above.
The wheel I had with that issue just did not seat at all when trying to set up the board, so being brand new it was easy to replace.
Also to note, I have seen wheels left with something sitting on them end up deformed too, like a board box or something a little heavier than normal and a set of wheels left under stuff in the car or where ever. One set that was skated a lot for a while, worn down a mm or two, then taken off and was in a car, then went to put back on and it was oval shaped. That happened to someone I know and it was the weirdest thing, as they were not new wheels, but we worked out that is what happened - had a full board box sitting on the wheel for a while and squashed it.
I put a well used old wheel in a vice once just to see and sure enough it flattened it from a nice round shape, that bounced back almost but not completely to more a slight oval when released, not that anyone should do something like that to good wheels.