(A lot of nice words, good points, and a good source)
Thanks man, it’s partially due to my being an engineer and having a large part of my work be experimental validation, and even more due to my wife having a PhD in biochemistry. She’s helped me make sense of a lot of this because biology and chemistry have always been areas I’m weak in.
So if omicron has only been found in vaccinated so far, how can a claim be made that unvaccinated caused the variant? I don’t understand that.
You’ve misunderstood, it hasn’t
only been found in vaccinated people, that is just the
first place it was found. That’s a bit like saying if AIDS was first found in 4 people that had tattoos, that tattoos caused it or only people with tattoos could get it. Omicron existed before those 4 people were infected, and has been found in both vaccinated and unvaccinated people since.
To understand how unvaccinated people led to omicron, I’ll try to briefly explain evolution. I’ll likely get some details slightly wrong, but the overall idea will be there.
Replicating DNA/RNA is hard and is usually not done perfectly. As such, every time that replication happens, so conception/birth of a human, or transmission of a virus, there is potential for the errors in replicating DNA/RNA to cause mutations. The more replications (generations), the more mutations happen. This is how evolution takes place, by the accumulation of these mutations.
Now the shorter the life span of an organism, the more replications take place, the more mutations happen. This is a bit of an oversimplification, but since viruses have a short life, they have a lot of replications compared to humans. They also rely on our cells to reproduce, which makes mutation even more likely, and means they can change that much quicker.
Now the reason this is important is because the more times a virus is transmitted, the more it mutates. This causes variants. With the previous studies I linked to, which I suggest you read, it is clear that transmission of far more likely to happen among unvaccinated people than vaccinated people.
Basically if you took the same virus and introduced it to a population that was vaccinated and a population that was unvaccinated, then came back in a month, the virus among the unvaccinated population would be vastly more mutated than the virus among the vaccinated population because it will have been transmitted many more times. That means that the virus in the vaccinated group would be very close to the original virus, but the one from the unvaccinated group would be different, and would be a variant.
That is how Delta and Omicron formed, by Covid infecting populations that had a very low vaccination rate, so it was transmitted a lot.
My reading on Fauci saying that vaccinated have as much virus in their nasopharynx as unvaccinated would support Jeremy’s opinion that both are equally able to spread covid.
There was one study that showed that the viral loads when first infected were similar between vaccinated and unvaccinated people, and this is what Fauci was referencing.
However, as the links I posted previously show, the viral load in vaccinated people drops far quicker than it does in unvaccinated people. This means that vaccinated people are infected, and thus contagious, for a far shorter period of time than unvaccinated people. That’s key, because if you see 10 people per day, and your infection lasts for 7 days less than an unvaccinated person, that’s 70 chances to transmit the virus that don’t exist. So that alone means that vaccinated people are less likely to transmit the virus.
However, the other links also showed that vaccinated people shed fewer infectious particles than unvaccinated people, and the particles they
do shed are less infectious.
All of this combines to make the chance of transmission far far lower for vaccinated people than unvaccinated people. This is actually pretty normal for vaccines.